ABC Heart Fail Cardiomyop 2022; 2(3): 259-267
Left Atrial Cardiomyopathy as a Generator of Heart Failure with Preserved Ejection Fraction
Antonio José Lagoeiro Jorge, Wolney de Andrade Martins, Evandro Tinoco Mesquita
, Marcio Roberto Moraes de Carvalho
Abstract
The left atrium is an anatomical structure relevant to the maintenance of the physiological hemodynamics of the cardiovascular system. Atrial cardiomyopathy (aCMP), defined as any change in the structure, architecture, contractility or electrophysiology of the atria, is associated with adverse clinical implications, and responsible for atrial fibrillation and stroke. Heart failure with preserved ejection fraction (HFpEF) with a predominance of atrial fibrillation (AF) is a unique clinical phenotype, characterized by mechanical dysfunction of the left atrium, congestive symptoms and poor prognosis. aCMP is a common condition among patients with HFpEF and AF. Due to the strong association between aCMP and HFpEF, the diagnosis of aCMP has clinical relevance in patients with HFpEF. The objective of this review is to help identify aCMP as a risk factor for the development of HFpEF.
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