Abstract Danon disease is a rare genetic disorder associated with mutations in the LAMP2 gene, located on the X chromosome, which encodes the LAMP2 protein that is essential for autophagy. The disease is characterized by a triad of cardiomyopathy, skeletal myopathy, and intellectual disability, with clinical manifestations that vary between the sexes. Men generally present with more severe and earlier forms, with hypertrophic cardiomyopathy and arrhythmias, whereas women present with later progression and less homogeneous symptoms. To illustrate the wide […]