Introduction Heart failure with preserved ejection fraction (HFpEF) is a complex clinical syndrome that has a negative impact on quality of life and life expectancy of patients, with high hospitalization and mortality rates. HFpEF is a highly prevalent disease, probably due to the increase in the prevalence of common risk factors, such as advanced age, female sex, arterial hypertension, diabetes, renal failure and obesity., It is estimated that nearly half of heart failure patients have preserved ejection fraction, defined as […]