Abstract Background: Benznidazole is the only drug against Trypanosoma cruzi (T. cruzi) available in Brazil. However, it has limited efficacy and frequent side effects. Recent studies suggest that ciprofloxacin hydrochloride, naproxen, and folic acid may have beneficial effects in treating the Chagas disease. Objective: To assess the in vitro parasiticidal action of ciprofloxacin, naproxen, and folic acid on the Y strain of T. cruzi, using benznidazole as a gold standard. Methods: Tablets of benznidazole, ciprofloxacin hydrochloride, naproxen, and folic acid […]