Abstract Background: The adherence to guideline-directed medical therapy in patients with heart failure (HF) remains suboptimal. Objectives: We evaluated the association between age and adherence to guideline-directed medical therapy in patients with chronic HF and explored whether polypharmacy and comorbidities might explain this association. Methods: We performed a cross-sectional study of 374 patients with chronic HF and left ventricle ejection fraction < 50% (23 to 89 years old, 33% women) between 2018 and 2019. GDMT was defined as using HF-related […]
