ABC Heart Fail Cardiomyop 2022; 2(2): 198-200
Dobutamine vs Milrinone in Heart Failure with Preserved Ejection Fraction: How do We Choose?
Heart failure (HF) occurs when the heart cannot pump sufficient blood to meet tissue needs and/or does so at the expense of high filling pressures, clinically manifesting itself through signs and symptoms of congestion and/or low cardiac output.
Decompensation is frequently observed in the condition’s natural history. Approximately 20% of HF exacerbations occur in low cardiac output syndrome, with cardiogenic shock being the most severe presentation. When there is evidence of poor organ perfusion, inotropes are fundamental pharmacological support, with dobutamine and milrinone being the most commonly used drugs.
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