ABC Heart Fail Cardiomyop 2021; 1(2): 161-166
Heart Failure Due to Cardiac Transthyretin Amyloidosis
Humberto Butzke da Motta
, Guilherme Oliveira Magalhães Costa
, Andreia Biolo
Abstract
A 90-year-old male patient presented with complaints and physical examination compatible with decompensated heart failure. Electrocardiogram showed atrial fibrillation and low voltage in limb leads, and echocardiogram identified biatrial dilatation, in addition to mild increases in ventricular wall thickness and diameter. Magnetic resonance imaging confirmed suspicion of cardiac amyloidosis. With negative serum and urinary protein electrophoresis and positive pyrophosphate cardiac scintigraphy, diagnosis of transthyretin cardiac amyloidosis was confirmed. Transthyretin gene mutations were not identified on sequencing, characterizing wild-type transthyretin cardiac amyloidosis.
Keywords: Amyloidosis; Heart Failure; Prealbumin
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