ABC Heart Fail Cardiomyop 2022; 2(3): 296-298

Pathophysiological Bases of Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction and Implications for Management

Aguinaldo F. Freitas Jr. ORCID logo , Daniela do Carmo Rassi Frota ORCID logo , Salvador Rassi ORCID logo

DOI: 10.36660/abchf.20220061

Pulmonary hypertension (PH) associated with left heart disease is classified as group 2, and it encompasses both heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF).1 In both diseases, the development of PH is associated with an unfavorable clinical course in the natural history of the disease, and knowledge about its pathophysiology is still uncertain, which may have practical implications from the diagnosis to the treatment of heart failure.2,3

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Pathophysiological Bases of Pulmonary Hypertension in Heart Failure with Preserved Ejection Fraction and Implications for Management

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